COVID-19: We are developing novel diagnostics and methods to mitigate the negative impact of the pandemic based on the fundamental pulmonary tissue biomechanics research conducted in our lab.
Check out our research
Welcome to bMECH
The bMECH lab sits at the interface of medicine and engineering. Our biomechanics research utilizes mechanical theory, experimental characterization, and computational modeling to explore the multiscale and adaptive response of biological systems. We focus on investigating pulmonary function through an engineering lens, seeking solutions to scientific questions surrounding lung disease. We aim to enable and develop predictive technologies and optimize innovative strategies for medical intervention.
Prof. Eskandari was invited as a plenary speaker to the International Living Heart and Virtual Twin for Humans Dassault Systèmes Symposium
Congrats! Crystal, Samaneh, and Mohammad's manuscript, titled "Novel Mechanical Strain Characterization of Ventilated Ex Vivo Porcine and Murine Lung Using Digital Image Correlation" has been published in Frontiers in Respiratory Physiology - (open access). We have established the foundation for linking local strains to global mechanics in the breathing lung, characterizing the regional response of the lung across various species, and contrasting healthy and pathological states. Thanks to our sponsors and our collaborators.
Prof. Eskandari was invited to present at the Beckman Research Institute at City of Hope's Department of Computational and Quantitative Medicine monthly seminar series
Prof. Eskandari was invited to share research findings at Univ. of California at Irvine's Department of Biomedical Engineering Seminar Series
Congrats! Samaneh, Crystal, and Swathi's manuscript, titled "Introducing a Custom-Designed Volume-Pressure Machine for Novel Measurements of Whole Lung Organ Viscoelasticity and Direct Comparisons Between Positive- and Negative-Pressure Ventilation" has been published in Frontiers in Bioengineering and Biotechnology - Biomechanics (open access). We have conceptualized and designed a novel system to measure the volume and pressure response of lungs, surpassing the capabilities of traditional machines and constructed to range mouse, pig, and human lung size-scales. Thanks to our collaborators, the Nordgren lab at UCR's School of Medicine and CellScale Biomaterials Testing
The bMECH lab was awarded an extramural grant for a lung structural biomechanics research project to improve ventilation strategies for pulmonary patients.
The Dean's Biomed Collaborative Grant from the School of Medicine was awarded to the bMECH lab to explore new techniques for diagnosing pulmonary disease.
Prof. Eskandari received the 2020 Distinguished Teaching Award
The UC National Laboratory Fees Research Grant was awarded to the bMECH lab. The initiative is aimed at rapidly supporting emergent research in areas
related to COVID-19.
Prof. Eskandari was awarded a plaque from UCR's University Honors Program for 2020 Faculty Mentor of the Year.
UCR Academic Senate awarded a Regent's Faculty Fellowship to Prof. Eskandari.
Our lab's lung mechanics research is supporting the fight against coronavirus as featured on UCR News: #COVID-19 highlights what we have yet to learn about lung mechanics
Samaneh's manuscript, titled "Characterizing the viscoelasticity of extra- and intra-parenchymal lung bronchi" has been published in the Journal of the Mechanical Behavior of Biomedical Materials (open access). This is the first study to investigate proximal and distal bronchial energy efficiency and contextualize tissue biochemical composition using rheological models. Results establish a foundation for future considerations of the role of viscoelasticity in diseased states. Congrats Samaneh!
Samaneh presented her research on the viscoelasticity of the bronchial network at the Inaugural Southern California Mechanics Workshop at UC San Diego.
Prof. Eskandari was invited to NSF's Computational Mechanics Vision Workshop at the University of Michigan.
Talha won a Presentation Award in the area of Engineering, Math, and Physics in addition to a travel grant to present his work on fiber imaging morphology at the 2019 Annual Biomedical Research Conference for Minority Students. Congrats Talha!
Latest research findings featured on UCR News: Crimped or Straight? Lung fiber shape influences elasticity: The shape and architecture of collagen and elastin fibers can improve our understanding of lung diseases, including the one associated with vaping
Ricardo and Talha presented their research on imaging bronchial tissues at the MSRIP Research Symposia at UC-Riverside and UC-San Diego
Prof. Eskandari was an Invited Speaker at the 16th International Symposium on Computer Methods in Biomechanics and Biomedical Engineering and the 4th Conference on Imaging and Visualization (CMBBE) at Columbia University, New York
bMECH's latest research findings published in Acta Biomaterialia is now available online. The link between structure and function is explored through constitutive modeling, biochemistry and histology
Our lab's research, featured on UCR News! UC Riverside research could eventually lead to advances in pulmonary healthcare: Scientists are just beginning to understand the mechanics of the lung
Samaneh received a travel grant to present her work on pulmonary viscoelasticity at the Summer of Biomechanics Biotransport and Bioengineering Conference (SB3C) in Seven Spring Pennsylvania. Congrats Samaneh!
Prof. Eskandari was recognized by the International Journal for Numerical Methods in Biomedical Engineering with the Best PhD Award
The bMECH lab and collaborators were awarded First Place in the category of Best Research Paper from the American Society of Engineering Education: "Provoked Emotion in Student Stories of Motivation Reveal Gendered Perceptions of What It Means to be Innovative in Engineering"
The Molecular and Translational Medicine Grant was awarded to the bMECH lab. The initiative, from the School of Medicine and Entrepreneurial Proof-of-Concept and Innovation Center at the University of California at Riverside, is aimed at catalyzing translational life-science research to improve the health of individuals by translating basic findings into future innovative diagnostics or therapeutics